Article
Combined assessment of EGFR pathway-related molecular markers and prognosis of NSCLC patients.
British journal of cancer - 13 Jan 2009
Galleges Ruiz M I, Floor K, Steinberg S M, Grünberg K, Thunnissen F B J M, Belien J A M, Meijer G A, Peters G J, Smit E F, Rodriguez J A, Giaccone G
Abstract excerpt
The purpose of this study is to evaluate the prognostic value of the combined assessment of multiple molecular markers related to the epidermal growth factor receptor (EGFR) pathway in resected non-small cell lung cancer (NSCLC) patients. Tumour specimens of 178 NSCLC patients were collected and analysed for EGFR and KRAS mutation status by DNA sequencing, and for EGFR copy number by fluorescent in situ...
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