Article
Tolerance versus immune response -- microRNAs as important elements in the regulation of the HLA-G gene expression.
Transplant immunology - 1 Mar 2009
Veit T D, Chies J A B
Abstract excerpt
HLA-G is a class Ib HLA which has gained much attention due to its multiple functions on the immune system. HLA-G exerts several immunomodulatory effects, being beneficially implicated in embryo implantation and fetal survival but, conversely, being potentially detrimental in tumors and viral infections. Such a two-edged sword behavior suggest that HLA-G expression is under tight regulation. However, to date,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
