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Heterozygous mutations of the sodium chloride cotransporter in Chinese children: prevalence and association with blood pressure.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Apr 2009

Hsu Yu-Juei, Yang Sung-Sen, Chu Nain-Feng, Sytwu Huey-Kang, Cheng Chih-Jen, Lin Shih-Hua

Abstract excerpt

BACKGROUND: Gitelman's syndrome (GS), which is caused by homozygous or compound heterozygous mutations of the thiazide-sensitive sodium chloride cotransporter (NCC), usually manifests in children and is associated with low blood pressure. However, the prevalence of heterozygous NCC mutations and their association with blood pressure in children have not yet been studied. METHODS: Five hundred unrelated children...

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PMID: 19033254
DOI: 10.1093/ndt/gfn619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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