Article
Lifetime reproductive success is maximized with optimal major histocompatibility complex diversity.
Proceedings. Biological sciences - 7 Mar 2009
Kalbe Martin, Eizaguirre Christophe, Dankert Ilka, Reusch Thorsten B H, Sommerfeld Ralf D, Wegner K Mathias, Milinski Manfred
Abstract excerpt
Individual diversity at the major histocompatibility complex (MHC) is predicted to be optimal at intermediate rather than at maximal levels. We showed previously in sticklebacks that an intermediate MHC diversity is predominant in natural populations and provides maximal resistance in experimental multiple parasite infections in the laboratory. However, what counts ultimately is the lifetime reproductive success...
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