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Article

Brachyury null mutant-induced defects in juvenile ascidian endodermal organs.

Development (Cambridge, England) - 1 Jan 2009

Chiba Shota, Jiang Di, Satoh Noriyuki, Smith William C

Abstract excerpt

We report the isolation of a recessive ENU-induced short-tailed mutant in the ascidian Ciona intestinalis that is the product of a premature stop in the brachyury gene. Notochord differentiation and morphogenesis are severely disrupted in the mutant line. At the larval stage, variable degrees of ectopic endoderm staining were observed in the homozygous mutants, indicating that loss of brachyury results in...

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Identifiers

PMID: 19019990
DOI: 10.1242/dev.030981
PMCID: PMC2685961

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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