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Article

The arflike gene encodes an essential GTP-binding protein in Drosophila.

Proceedings of the National Academy of Sciences of the United States of America - 15 Apr 1991

Tamkun J W, Kahn R A, Kissinger M, Brizuela B J, Rulka C, Scott M P, Kennison J A

Abstract excerpt

We have identified a Drosophila gene (arflike, arl) encoding a protein that is structurally related (approximately 55% identity) to the ADP-ribosylation factors (ARFs) of yeast and mammals. Biochemical analyses of purified recombinant arl-encoded protein revealed properties similar to the ARF proteins, including the ability to bind and hydrolyze GTP. Clear functional differences between arl and ARF proteins,...

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Identifiers

PMID: 1901655
DOI: 10.1073/pnas.88.8.3120
PMCID: PMC51397

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