Article
Assessment of allelic diversity in intron-containing Mal d 1 genes and their association to apple allergenicity.
BMC plant biology - 13 Nov 2008
Gao Zhongshan, van de Weg Eric W, Matos Catarina I, Arens Paul, Bolhaar Suzanne T H P, Knulst Andre C, Li Yinghui, Hoffmann-Sommergruber Karin, Gilissen Luud J W J
Abstract excerpt
BACKGROUND: Mal d 1 is a major apple allergen causing food allergic symptoms of the oral allergy syndrome (OAS) in birch-pollen sensitised patients. The Mal d 1 gene family is known to have at least 7 intron-containing and 11 intronless members that have been mapped in clusters on three linkage groups. In this study, the allelic diversity of the seven intron-containing Mal d 1 genes was assessed among a set of...
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