Article
ERCC1 polymorphism, expression and clinical outcome of oxaliplatin-based adjuvant chemotherapy in gastric cancer.
World journal of gastroenterology - 7 Nov 2008
Huang Zhao-Hui, Hua Dong, Du Xiang, Li Li-Hua, Mao Yong, Liu Zhi-Hui, Song Ming-Xu, Zhou Xi-Ke
Abstract excerpt
AIM: To determine the influence of excision repair cross complementing group 1 (ERCC1) codon 118 polymorphism and mRNA level on the clinical outcome of gastric cancer patients treated with oxaliplatin-based adjuvant chemotherapy. METHODS: Eighty-nine gastric cancer patients treated with oxalipatin-based adjuvant chemotherapy were included in this study. ERCC1 codon 118 C/T polymorphism was tested by polymerase...
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