Monitoring of gliomas <i>in vivo</i> by diffusion MRI and ¹H MRS during gene therapy‐induced apoptosis: interrelationships between water diffusion and mobile lipids

Abstract excerpt

The measurement of water diffusion by diffusion-weighted MRI (DWI) in vivo offers a non-invasive method for assessing tissue responses to anti-cancer therapies. The pathway of cell death after anti-cancer treatment is often apoptosis, which leads to accumulation of mobile lipids detectable by (1)H MRS in vivo. However, it is not known how these discrete MR markers of cell death relate to each other. In a rodent...

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