Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Marineosins A and B, Cytotoxic Spiroaminals from a Marine-Derived Actinomycete

13 Nov 2008

Abstract excerpt

Two novel spiroaminals, marineosins A and B (1, 2), containing two pyrrole functionalities, were isolated from cultures of a marine sediment-derived actinomycete related to the genus Streptomyces. The marineosins, which appear to be derived from unknown modifications of prodigiosin-like pigment pathways, showed significant inhibition of human colon carcinoma (HCT-116) in an in vitro assay (IC50 = 0.5 microM for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Marine Sponges and Natural Products
Share to Microbial Metabolism and Applications
Share to Microbial Natural Products and Biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19007176
DOI: 10.1021/ol8020644

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Marineosins A and B, Cytotoxic Spiroaminals from a Marine-Derived ActinomycetePMID 19007176Read ↗

Secondary Metabolites from Marine-Derived Fungi and Actinobacteria as Potential Sources of Novel Colorectal Cancer DrugsSemantic proximity Read ↗

Natural Products from Actinobacteria as a Potential Source of New Therapies Against Colorectal Cancer: A ReviewSemantic proximity Read ↗

Decylprodigiosin: a new member of the prodigiosin family isolated from a seaweed-associated StreptomycesSemantic proximity Read ↗

Natural Products from Actinomycetes Associated with Marine OrganismsSemantic proximity Read ↗

Marine-derived fungi: a chemically and biologically diverse group of microorganismsSemantic proximity Read ↗

Monacycliones G–K and ent-Gephyromycin A, Angucycline Derivatives from the Marine-Derived Streptomyces sp. HDN15129Semantic proximity Read ↗

Neo-actinomycins A and B, natural actinomycins bearing the 5H-oxazolo[4,5-b]phenoxazine chromophore, from the marine-derived Streptomyces sp. IMB094Semantic proximity Read ↗

Can Some Marine-Derived Fungal Metabolites Become Actual Anticancer Agents?Semantic proximity Read ↗

Neoantimycins A and B, Two Unusual Benzamido Nine-Membered Dilactones from Marine-Derived Streptomyces antibioticus H12-15Semantic proximity Read ↗

Antibacterial and Cytotoxic New Napyradiomycins from the Marine-Derived Streptomyces sp. SCSIO 10428Semantic proximity Read ↗

Actinomycetes for Marine Drug Discovery Isolated from Mangrove Soils and Plants in ChinaSemantic proximity Read ↗

Exceptional production of both prodigiosin and cycloprodigiosin as major metabolic constituents by a novel marine bacterium, Zooshikella rubidus S1-1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.