Article
[Molecular genetic method of rapid detection of Bordetella pertussis strains are possessed of different ptx genes].
Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 Jan 2000
Borisova O Iu, Kombarova S Iu, Gadua N T, Mazurova I K
Abstract excerpt
Features of structure of different B. pertussis genes are studied in many countries of the world, and, first of all, ptxA gene, which encodes main protective antigen of the microbe--pertussis toxin. Starting from 1980s, B. pertussis strains with new "non-vaccine" allele ptxA1 gradually displaced strains with old "vaccine" alleles--ptxA2 and ptxA4, and now the formers dominate in circulating bacterial population....
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