Article
Critical role of PBEF expression in pulmonary cell inflammation and permeability.
Cell biology international - 1 Jan 2009
Liu Peng, Li Hailong, Cepeda Javier, Zhang Li Qin, Cui Xiuyun, Garcia Joe G N, Ye Shui Qing
Abstract excerpt
Previous studies in our lab have identified pre-B-cell colony enhancing factor (PBEF) as a novel biomarker in acute lung injury. This study continues to elucidate the underlying molecular mechanism of PBEF in the pathogenesis of acute lung injury in pulmonary cell culture models. Our results revealed that IL-1beta induced PBEF expression in pulmonary vascular endothelial cells at the transcriptional level and a...
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