Article
Effect of Helicobacter pylori infection on IL-8, IL-1beta and COX-2 expression in patients with chronic gastritis and gastric cancer.
Scandinavian journal of gastroenterology - 1 Jan 2009
Bartchewsky Waldemar, Martini Mariana Rocha, Masiero Mariana, Squassoni Aline Candido, Alvarez Marisa Claudia, Ladeira Marcelo Sady, Salvatore Daisy, Trevisan Miriam, Pedrazzoli José, Ribeiro Marcelo Lima
Abstract excerpt
OBJECTIVE: Helicobacter pylori infection is related to gastric cancer development, and chronic inflammation is presumed to be the main cause. The aim of the present study was to evaluate the influence of H. pylori cagA, vacA, iceA, and babA genotypes on COX-2, IL-1beta, and IL-8 expression. MATERIAL AND METHODS: Of the 217 patients included in the study, 26 were uninfected, 127 had chronic gastritis and were H....
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