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Article

One third of Japanese patients with multiple osteochondromas may have mutations in genes other than EXT1 or EXT2.

Genetic testing - 1 Dec 2008

Kojima Hirofumi, Wada Takahito, Seki Hiroshi, Kubota Takeo, Wakui Keiko, Fukushima Yoshimitsu

Abstract excerpt

Multiple osteochondromas (MO; also referred to as hereditary multiple exostoses [HME] in the literature) is an autosomal dominant disorder characterized by benign, cartilage-capped bone tumors that grow from the metaphyses of long bones. Two genes are associated with this disease: EXT1 on 8q24.11...

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Source

Identifiers

PMID: 18976157
DOI: 10.1089/gte.2008.0048

Genes

EXT1
EXT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18976157-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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One third of Japanese patients with multiple osteochondromas may have mutations in genes other than EXT1 or EXT2.PMID 18976157Read ↗

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