Article
Androgen receptor repeat length polymorphism associated with male-to-female transsexualism.
Biological psychiatry - 1 Jan 2009
Hare Lauren, Bernard Pascal, Sánchez Francisco J, Baird Paul N, Vilain Eric, Kennedy Trudy, Harley Vincent R
Abstract excerpt
BACKGROUND: There is a likely genetic component to transsexualism, and genes involved in sex steroidogenesis are good candidates. We explored the specific hypothesis that male-to-female transsexualism is associated with gene variants responsible for undermasculinization and/or feminization. Specifically, we assessed the role of disease-associated repeat length polymorphisms in the androgen receptor (AR), estrogen...
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