Article
Low frequency of precore mutants in anti-hepatitis B e antigen positive subjects with chronic hepatitis B virus infection in Chennai, Southern India.
Journal of microbiology and biotechnology - 1 Oct 2008
Shanmugam Saravanan, Velu Vijayakumar, Nandakumar Subhadra, Madhavan Vidya, Shanmugasundaram Uma, Shankar Esaki Muthu, Murugavel Kailapuri G, Balakrishnan Pachamuthu, Kumarasamy Nagalingeswaran, Solomon Suniti, Thyagarajan Sadras Panchatcharam
Abstract excerpt
The natural course of chronic hepatitis B (CH-B) virus infection is reportedly variable, and the long-term outcomes in hepatitis B e antigen (HBeAg)-negative chronic hepatitis B infection are distinct from HBeAg-positive chronic hepatitis. However, the molecular virological factors that contribute to the progression of liver disease in the south Indian setting remain largely unclear. We prospectively studied 679...
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