Article
Oxidative imbalance in idiopathic renal hypouricemia.
Pediatric nephrology (Berlin, Germany) - 1 Apr 2009
Kaneko Kazunari, Taniguchi Naho, Tanabe Yuko, Nakano Takahide, Hasui Masafumi, Nozu Kandai
Abstract excerpt
An important complication of idiopathic renal hypouricemia is exercise-induced acute renal failure (ARF). The most plausible explanation for this complication is that decreased antioxidant potential leads to kidney injury by reactive oxygen species (ROS). We demonstrated this oxidative imbalance by a concomitant assessment of ROS production and antioxidant system capability in a 15- year-old girl with idiopathic...
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