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Article

Genetic variation in ABC G5/G8 and NPC1L1 impact cholesterol response to plant sterols in hypercholesterolemic men.

Lipids - 1 Dec 2008

Zhao Hai L, Houweling Adrielle H, Vanstone Catherine A, Jew Stephanie, Trautwein Elke A, Duchateau Guus S M J E, Jones Peter J H

Abstract excerpt

ATP-binding cassette hetero-dimeric transporters G5 and G8 (ABCG5/G8) have been postulated to mediate intestinal cholesterol efflux, whereas Niemann-Pick C1 Like 1 (NPC1L1) protein is believed to be essential for intestinal cholesterol influx. The individual or combined genetic markers, such as s...

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Source

Identifiers

PMID: 18850127
DOI: 10.1007/s11745-008-3241-y

Genes

ABCG5
ABCG8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18850127-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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