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Article

No association of PTPN1 polymorphisms with macronutrient intake and measures of adiposity.

Obesity (Silver Spring, Md.) - 1 Dec 2008

Bauer Florianne, Onland-Moret N Charlotte, Niehoff Anne G, Elbers Clara C, Grobbee Diederick E, Wijmenga Cisca, van der Schouw Yvonne T

Abstract excerpt

The protein tyrosine phosphatase nonreceptor type1 (PTPN1) gene encodes for the protein tyrosine phosphatase 1B, which suppresses the signaling pathway of leptin. Variations of the PTPN1 gene may lead to changes in leptin sensitivity and thereby influence eating behavior and measures of obesity. This study investigated the association between single-nucleotide polymorphisms (SNPs) of the PTPN1 gene and eating...

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Source

Identifiers

PMID: 18846048
DOI: 10.1038/oby.2008.426

Genes

PTPN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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