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Article

Gene-environment contributions to the development of infant vagal reactivity: the interaction of dopamine and maternal sensitivity.

Child development - 1 Jan 2000

Propper Cathi, Moore Ginger A, Mills-Koonce W Roger, Halpern Carolyn Tucker, Hill-Soderlund Ashley L, Calkins Susan D, Carbone Mary Anna, Cox Martha

Abstract excerpt

This study investigated dopamine receptor genes (DRD2 and DRD4) and maternal sensitivity as predictors of infant respiratory sinus arrhythmia (RSA) and RSA reactivity, purported indices of vagal tone and vagal regulation, in a challenge task at 3, 6, and 12 months in 173 infant-mother dyads. Hierarchical linear modeling (HLM) revealed that at 3 and 6 months, RSA withdrawal in response to maternal separation was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18826531
DOI: 10.1111/j.1467-8624.2008.01194.x

Genes

DRD2
DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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