Article
Highly divergent molecular variants of human T-lymphotropic virus type I from isolated populations in Papua New Guinea and the Solomon Islands.
Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 1991
Gessian A, Yanagihara R, Franchini G, Garruto R M, Jenkins C L, Ajdukiewicz A B, Gallo R C, Gajdusek D C
Abstract excerpt
To determine the molecular genetic relationship between Melanesian strains of human T-lymphotropic virus type I (HTLV-I) and cosmopolitan prototype HTLV-I, we amplified by PCR, then cloned, and sequenced a 522-base-pair region of the HTLV-I env gene in DNA extracted from uncultured (fresh) and cu...
Topics
- Adult
- Amino Acid Sequence
- Base Sequence
- DNA, Viral
- Female
- Gene Products, env
- Genes, Viral
- Genes, env
- Genetic Variation
- Human T-lymphotropic virus 1
- Humans
- Male
- Melanesia
- Middle Aged