Article
Monocytes and their pathophysiological role in Crohn's disease.
Cellular and molecular life sciences : CMLS - 1 Jan 2009
Zhou L, Braat H, Faber K N, Dijkstra G, Peppelenbosch M P
Abstract excerpt
Our immune system shows a stringent dichotomy, on the one hand displaying tolerance towards commensal bacteria, but on the other hand vigorously combating pathogens. Under normal conditions the balance between flora tolerance and active immunity is maintained via a plethora of dynamic feedback mechanisms. If, however, the balancing act goes faulty, an inappropriate immune reaction towards an otherwise harmless...
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