Article
[Pharmacogenetics and treatment response in schizophrenia].
L'Encephale - 1 Dec 2007
Moulier V, Januel D
Abstract excerpt
UNLABELLED: The pharmacogenetic strategy uses the genetic association approach with the aim of identifying genes that influence clinical response to drug treatment. Association studies have focused mainly on neuroleptics (in particular clozapine) and variants in candidate genes of dopamine and serotonin systems in schizophrenic patients. Concerning the serotonin 5-HT(2A) receptor gene, the frequency of allele...
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