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Article

Kaposi’s sarcoma-associated herpesvirus RTA activates the processivity factor ORF59 through interaction with RBP-Jκ and a cis-acting RTA responsive element

11 Sept 2008

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PMID: 18786687
DOI: 10.1016/j.virol.2008.08.011

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Kaposi’s sarcoma-associated herpesvirus RTA activates the processivity factor ORF59 through interaction with RBP-Jκ and a cis-acting RTA responsive elementPMID 18786687Read ↗

The role of Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8 regulator of transcription activation (RTA) in control of gene expressionSemantic proximity Read ↗

Comparative Study of Regulation of RTA-Responsive Genes in Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8Semantic proximity Read ↗

Kaposi's Sarcoma-Associated Herpesvirus Processivity Factor, ORF59, Binds to Canonical and Linker Histones, and Its Carboxy Terminus Is Dispensable for Viral DNA Synthesis.Semantic proximity Read ↗

Interaction of Kaposi's Sarcoma-Associated Herpesvirus ORF59 with oriLyt Is Dependent on Binding with K-RtaSemantic proximity Read ↗

Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) replication and transcription factor activates the K9 (vIRF) gene through two distinct cis elements by a non-DNA-binding mechanism.Semantic proximity Read ↗

Amplification of the Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 lytic origin of DNA replication is dependent upon a cis-acting AT-rich region and an ORF50 response element and the trans-acting factors ORF50 (K-Rta) and K8 (K-bZIP)Semantic proximity Read ↗

Wide-Scale Use of Notch Signaling Factor CSL/RBP-Jκ in RTA-Mediated Activation of Kaposi's Sarcoma-Associated Herpesvirus Lytic GenesSemantic proximity Read ↗

Direct interactions of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 ORF50/Rta protein with the cellular protein octamer-1 and DNA are critical for specifying transactivation of a delayed-early promoter and stimulating viral reactivation.Semantic proximity Read ↗

Kaposi's Sarcoma-associated Herpesvirus Open Reading Frame 50 Stimulates the Transcriptional Activity of STAT3Semantic proximity Read ↗

Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8 ORF50 gene product contains a potent C-terminal activation domain which activates gene expression via a specific target sequenceSemantic proximity Read ↗

NF-κB Serves as a Cellular Sensor of Kaposi's Sarcoma-Associated Herpesvirus Latency and Negatively Regulates K-Rta by Antagonizing the RBP-Jκ CoactivatorSemantic proximity Read ↗

The T Cell Activation Factor NF-ATc Positively Regulates HIV-1 Replication and Gene Expression in T CellsSemantic proximity Read ↗

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