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Article

The role of Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8 regulator of transcription activation (RTA) in control of gene expression

11 Aug 2003

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PMID: 12910252
DOI: 10.1038/sj.onc.1206555

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The role of Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8 regulator of transcription activation (RTA) in control of gene expressionPMID 12910252Read ↗

Comparative Study of Regulation of RTA-Responsive Genes in Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8Semantic proximity Read ↗

Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8 ORF50 gene product contains a potent C-terminal activation domain which activates gene expression via a specific target sequenceSemantic proximity Read ↗

Amplification of the Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 lytic origin of DNA replication is dependent upon a cis-acting AT-rich region and an ORF50 response element and the trans-acting factors ORF50 (K-Rta) and K8 (K-bZIP)Semantic proximity Read ↗

Kaposi’s sarcoma-associated herpesvirus RTA activates the processivity factor ORF59 through interaction with RBP-Jκ and a cis-acting RTA responsive elementSemantic proximity Read ↗

Gene Induction Pathways Mediated by Distinct IRFs during Viral InfectionSemantic proximity Read ↗

A viral gene that activates lytic cycle expression of Kaposi’s sarcoma-associated herpesvirusSemantic proximity Read ↗

Auto-activation of the rta gene of human herpesvirus-8/Kaposi’s sarcoma-associated herpesvirusSemantic proximity Read ↗

Innate and Adaptive Factors Regulating Human Immunodeficiency Virus Type 1 Genomic ActivationSemantic proximity Read ↗

Direct interactions of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 ORF50/Rta protein with the cellular protein octamer-1 and DNA are critical for specifying transactivation of a delayed-early promoter and stimulating viral reactivation.Semantic proximity Read ↗

The T Cell Activation Factor NF-ATc Positively Regulates HIV-1 Replication and Gene Expression in T CellsSemantic proximity Read ↗

Cellular Transcription Factors Involved in the Regulation of HIV-1 Gene ExpressionSemantic proximity Read ↗

Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) replication and transcription factor activates the K9 (vIRF) gene through two distinct cis elements by a non-DNA-binding mechanism.Semantic proximity Read ↗

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