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Article

Decreased expression of autophagy-related proteins in malignant epithelial ovarian cancer

16 Nov 2008

Abstract excerpt

Some studies have shown that the change of autophagic capacity may correlate with malignant transformation. Our study was designed to investigate the expression and significance of two autophagy-related proteins, microtubule-associated protein 1 light chain 3 (LC3) and Beclin 1 in the tumorigenesis and development of epithelial ovarian carcinoma. We observed that the positive expression of LC3 and Beclin 1 was...

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PMID: 18776739
DOI: 10.4161/auto.6827

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