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Article

Analysis of the RET gene in subjects with sporadic Hirschsprung's disease.

Journal of the Chinese Medical Association : JCMA - 1 Aug 2008

Chin Tai-Wai, Chiu Chih-Yang, Tsai Hsin-Lin, Liu Chin-Su, Wei Chou-Fu, Jap Tjin-Shing

Abstract excerpt

BACKGROUND: Hirschsprung's disease (HSCR), or aganglionic megacolon, is a hereditable disease of the enteric nervous system. It is an embryonic developmental disorder characterized by the absence of ganglion cells in the lower enteric plexus. Gut motility is compromised in HSCR, with consequent risk of intestinal obstruction. METHODS: We sequenced the RET gene and characterized the clinical manifestations in 15...

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Identifiers

PMID: 18772120
DOI: 10.1016/S1726-4901(08)70091-1

Genes

RET

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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