Article
Immunological profile of a Plasmodium vivax AMA-1 N-terminus peptide-carbon nanotube conjugate in an infected Plasmodium berghei mouse model.
Vaccine - 29 Oct 2008
Yandar Nubia, Pastorin Giorgia, Prato Maurizio, Bianco Alberto, Patarroyo Manuel Elkin, Lozano José Manuel
Abstract excerpt
We have covalently conjugated an N-terminus Plasmodium vivax apical membrane antigen-1 (AMA-1) peptide to functionalized carbon nanotubes (f-CNT). Immunological characterization of this molecular conjugate revealed that the immunogen-AMA-1 peptide was appropriately presented after being conjugated to CNTs as well as being recognized by BALB/c polyclonal antibodies. Subsequent experiments lead us to assess the...
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