Article
Aged keratinocyte phenotyping: morphology, biochemical markers and effects of Dead Sea minerals.
Experimental gerontology - 1 Oct 2008
Soroka Yoram, Ma'or Zeev, Leshem Yael, Verochovsky Lilian, Neuman Rami, Brégégère François Menahem, Milner Yoram
Abstract excerpt
The aging process and its characterization in keratinocytes have not been studied in depth until now. We have assessed the cellular and molecular characteristics of aged epidermal keratinocytes in monolayer cultures and in skin by measuring their morphological, fluorometric and biochemical properties. Light and electron microscopy, as well as flow cytometry, revealed increase in cell size, changes in cell shape,...
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