Article
Changes in the adhesive phenotype of regional lymphocytes in rats with adjuvant arthritis: alteration by cyclophosphamide.
Methods and findings in experimental and clinical pharmacology - 1 May 1991
Altankov G, Marinova-Mutafchieva L, Nikolaeva N, Penkova R
Abstract excerpt
A quantitative spectrophotometrical method was used to study the adhesive phenotype of lymphocytes from regional lymph nodes of rats with early stage adjuvant-induced arthritis (AA), pretreated or not with cyclophosphamide (CY). The results showed that adhesion of lymphocytes from AA-sensitized lymph nodes to gelatin and collagens (type I, II, III and IV) was enhanced, especially to collagen type II. However,...
Topics
- Animals
- Arthritis, Experimental
- Cell Adhesion
- Cyclophosphamide
- Lymph Nodes
- Lymphocytes
- Male
- Phenotype
- Rats
- Rats, Inbred Strains
- Time Factors