The role of adhesion molecules in allergic inflammation and their suitability as targets of antiallergic therapy.

Abstract excerpt

Adhesion molecules on leukocytes and tissue-resident cells are now known to mediate steps of the allergic inflammation response. Blockade of adhesion pathways is being actively explored as a potential strategy to therapeutically manage allergic diseases. The various adhesion molecules and their counterligands are discussed with respect to evidence supporting their role in allergic inflammation and suitability as...

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