Article
The role of adhesion molecules in allergic inflammation and their suitability as targets of antiallergic therapy.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Aug 1998
Schleimer R P, Bochner B S
Abstract excerpt
Adhesion molecules on leukocytes and tissue-resident cells are now known to mediate steps of the allergic inflammation response. Blockade of adhesion pathways is being actively explored as a potential strategy to therapeutically manage allergic diseases. The various adhesion molecules and their c...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, CD
- Asthma
- Cell Adhesion Molecules
- Guinea Pigs
- Haplorhini
- Humans
- Hypersensitivity
- Integrins
- Intercellular Adhesion Molecule-1
- Leukocyte-Adhesion Deficiency Syndrome
- Mice
- Mice, Knockout
- Phenotype
- Platelet Endothelial Cell Adhesion Molecule-1
- Rabbits
- Rats