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Article

Puzzles, promises and a cure for ageing.

Nature - 28 Aug 2008

Vijg Jan, Campisi Judith

Abstract excerpt

Recent discoveries in the science of ageing indicate that lifespan in model organisms such as yeast, nematodes, flies and mice is plastic and can be manipulated by genetic, nutritional or pharmacological intervention. A better understanding of the targets of such interventions, as well as the proximate causes of ageing-related degeneration and disease, is essential before we can evaluate if abrogation of human...

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Identifiers

PMID: 18756247
DOI: 10.1038/nature07216
PMCID: PMC2774752

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