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<i>Toxoplasma</i>and reaction time: role of toxoplasmosis in the origin, preservation and geographical distribution of Rh blood group polymorphism

28 Aug 2008

Abstract excerpt

The RhD protein which is the RHD gene product and a major component of the Rh blood group system carries the strongest blood group immunogen, the D-antigen. This antigen is absent in a significant minority of the human population (RhD-negatives) due to RHD deletion or alternation. The origin and persistence of this RhD polymorphism is an old evolutionary enigma. Before the advent of modern medicine, the carriers...

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PMID: 18752708
DOI: 10.1017/s003118200800485x

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