Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metabolism of curcumin and induction of mitotic catastrophe in human cancer cells

20 Aug 2008

Abstract excerpt

In cultured cells, curcumin (CUR) causes cell death by interfering with mitosis and leading to fragmented nuclei and disrupted microtubules, a process named mitotic catastrophe. In order to clarify the role of the known CUR metabolites hexahydro-CUR (HHC) and CUR-glucuronide (CUR-gluc) in mitotic catastrophe, the effects of CUR were studied in three human cancer cell lines with different metabolism of CUR. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Curcumin's Biomedical Applications
Share to Drug Transport and Resistance Mechanisms
Share to Retinoids in leukemia and cellular processes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18720347
DOI: 10.1002/mnfr.200800029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Metabolism of curcumin and induction of mitotic catastrophe in human cancer cellsPMID 18720347Read ↗

Mechanisms of drug-induced mitotic catastrophe in cancer cells.Semantic proximity Read ↗

A link between mitotic defects and mitotic catastrophe: detection and cell fateSemantic proximity Read ↗

Quinalizarin induces autophagy, apoptosis and mitotic catastrophe in cervical and prostate cancer cellsSemantic proximity Read ↗

Colchicine: Isolation, LC–MS QTof Screening, and Anticancer Activity Study of Gloriosa superba SeedsSemantic proximity Read ↗

Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cellsSemantic proximity Read ↗

Ceramide involvement in homocamptothecin- and camptothecin-induced cytotoxicity and apoptosis in colon HT29 cells.Semantic proximity Read ↗

Induction of mammalian cell transformation and genotoxicity by 2-methoxyestradiol, an endogenous metabolite of estrogen.Semantic proximity Read ↗

Mitotic catastrophe and cancer drug resistance: A link that must to be broken.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.