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Article

Human type VII collagen: cDNA cloning and chromosomal mapping of the gene.

15 Aug 1991

Abstract excerpt

A human keratinocyte cDNA expression library in bacteriophage lambda gt11 was screened with the purified IgG fraction of serum from a patient with epidermolysis bullosa acquisita, which had a high titer of anti-type VII collagen antibodies. Screening of approximately 3 x 10(5) plaques identified 8 positive clones, the largest one (K-131) being approximately 1.9 kilobases in size. Dideoxynucleotide sequencing of...

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Identifiers

PMID: 1871109
DOI: 10.1073/pnas.88.16.6931

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Human type VII collagen: cDNA cloning and chromosomal mapping of the gene.PMID 1871109Read ↗

Cloning of human type VII collagen. Complete primary sequence of the alpha 1(VII) chain and identification of intragenic polymorphisms.Semantic proximity Read ↗

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Type VII collagen: the anchoring fibril protein at fault in dystrophic epidermolysis bullosa.Semantic proximity Read ↗

The recombinant expression of full-length type VII collagen and characterization of molecular mechanisms underlying dystrophic epidermolysis bullosa.Semantic proximity Read ↗

Molecular basis for the dystrophic forms of epidermolysis bullosa: mutations in the type VII collagen gene.Semantic proximity Read ↗

Type VII collagen gene expression by cultured human cells and in fetal skin. Abundant mRNA and protein levels in epidermal keratinocytes.Semantic proximity Read ↗

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Genetic basis of Bart's syndrome: a glycine substitution mutation in the type VII collagen gene.Semantic proximity Read ↗

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