Article
Molecular epidemiology of dengue virus serotypes 2 and 3 in Paraguay during 2001-2006: the association of viral clade introductions with shifting serotype dominance.
Virus research - 1 Nov 2008
Aquino Jose D J Diaz, Tang Wei-Feng, Ishii Ryoichi, Ono Tetsuro, Eshita Yuki, Aono Hiroshi, Makino Yoshihiro
Abstract excerpt
To determine the genetic variability of dengue viruses (DENVs) in Paraguay, the complete envelope gene was sequenced for 4 DENV-2 and 22 DENV-3 strains isolated from 2001 to 2006. The sequence data were used in Bayesian phylogenetic analyses, which revealed that Paraguayan DENV-2 strains fell into two distinct clades within the American/Asian genotype, thus suggesting that the introduction of a new DENV-2 clade...
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