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Molecular characterization of dengue virus reveals regional diversification of serotype 2 in Colombia

8 May 2019

Abstract excerpt

Dengue is hyperendemic in Colombia, where a cyclic behavior of serotype replacement leading to periodic epidemics has been observed for decades. This level of endemicity favors accumulation of dengue virus genetic diversity and could be linked to disease outcome. To assess the genetic diversity of dengue virus type 2 in Colombia, we sequenced the envelope gene of 24 virus isolates from acute cases of dengue or...

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PMID: 31068191
DOI: 10.1186/s12985-019-1170-4

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