Serum transferrin saturation increase is associated with decrease of antibacterial activity of serum in patients with HFE-related genetic hemochromatosis.

doi:10.1111/j.1572-0241.2008.02036.x

Article

Serum transferrin saturation increase is associated with decrease of antibacterial activity of serum in patients with HFE-related genetic hemochromatosis.

The American journal of gastroenterology - 1 Oct 2008

Jolivet-Gougeon Anne, Loréal Olivier, Ingels Anne, Danic Bruno, Ropert Martine, Bardou-Jacquet Edouard, Aqodad Nourdin, Aussant-Bertel Françoise, Ferec Claude, Brissot Pierre

Abstract excerpt

OBJECTIVES: Patients with type 1 (HFE-related) genetic hemochromatosis are usually excluded from blood donation on the basis that this disease may facilitate bacterial infections. The aim of the present study was to evaluate the serum antibacterial effect against Salmonella enterica Typhimurium LT2 in relation to iron status. METHODS: Serum samples were collected in 26 iron-overloaded (homozygous C282Y mutation)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Histocompatibility Antigens Class I

Share to Nephelometry and Turbidimetry

Share to Salmonella Infections

Share to Salmonella typhimurium

Share to Serum

Share to Transferrin

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest

Serum transferrin saturation increase is associated with decrease of antibacterial activity of serum in patients with HFE-related genetic hemochromatosis.PMID 18684194Read

Genetic and Dietary Iron Overload Differentially Affect the Course of Salmonella Typhimurium InfectionSemantic proximity Read

Wild-type HFE protein normalizes transferrin iron accumulation in macrophages from subjects with hereditary hemochromatosisSemantic proximity Read

EASL clinical practice guidelines for HFE hemochromatosis.Semantic proximity Read

Review article: the iron overload syndromes.Semantic proximity Read

Iron, hemochromatosis genotypes, and risk of infections: a cohort study of 142 188 general population individuals.Semantic proximity Read

Hereditary Hemochromatosis – How Not to Overlook and Properly Manage “Iron People”- a Critical OverviewSemantic proximity Read

Hereditary haemochromatosis.Semantic proximity Read

[Hemochromatosis--from an underdiagnosed curiosity to a common disease].Semantic proximity Read