Article
[Codon modification of HIV-1 subtype B gag gene and its immunogenicity in mice].
Bing du xue bao = Chinese journal of virology - 1 May 2008
Feng Xia, Yu Shuang-Qing, Liu Hong-Mei, Liu Xin-Lei, Wang Xiao-Li, Zhou Ling, Zeng Yi
Abstract excerpt
HIV-1 subtype B gag genes were cloned from the infected paid blood donors in Henan, and the consensus sequence based on these prevalent strains was obtained by aligning. The codons of the consensus gag sequence were modified according to mammalian codon usage. Western blot analysis was used to compare the expression level of wild type and codon-modified gag gene. It was found that the expression level of Gag...
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