Low activation of Insulin-like Growth Factor 1-Receptor (IGF1R) is associated with local recurrence in early breast carcinoma.

doi:10.1007/s10549-008-0139-6

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Low activation of Insulin-like Growth Factor 1-Receptor (IGF1R) is associated with local recurrence in early breast carcinoma.

Breast cancer research and treatment - 1 Sept 2009

Peiró Gloria, Benlloch Susana, Sánchez-Tejada Laura, Adrover Encarna, Lerma Enrique, Peiró Francisca M, Sánchez-Payá José, Aranda F Ignacio

Abstract excerpt

Background The predictive value of IGF1R on local recurrence in invasive breast carcinoma (BC) is not well known. Methods In a series of 197 lymph-node negative BC patients treated with breast-conserving surgery and radiation therapy, we performed immunohistochemistry for alpha-IGF1R, beta-IGF1R...

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Low activation of Insulin-like Growth Factor 1-Receptor (IGF1R) is associated with local recurrence in early breast carcinoma.

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