Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Low prevalence of MODY2 and MODY3 mutations in Brazilian individuals with clinical MODY phenotype.

Diabetes research and clinical practice - 1 Sept 2008

Furuzawa Gilberto K, Giuffrida Fernando M A, Oliveira Carolina S V, Chacra Antonio R, Dib Sergio A, Reis André F

Abstract excerpt

Prevalence of MODY2 and MODY3 mutations has been assessed in 23 Brazilian families with MODY phenotype. Mutations in HNF-1alpha have been found in 3 families (13%) and 2 families (8.7%) had new glucokinase mutations. These genes do not explain the majority of MODY cases in Brazilian population.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Brazil
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Glucokinase

Share to Hepatocyte Nuclear Factor 1-alpha

Share to Prevalence

Source

Identifiers

PMID: 18672310
DOI: 10.1016/j.diabres.2008.06.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Low prevalence of MODY2 and MODY3 mutations in Brazilian individuals with clinical MODY phenotype.PMID 18672310Read ↗

Novel insights into genetics and clinics of the HNF1A-MODYSemantic proximity Read ↗

The spectrum of HNF1A gene mutations in Greek patients with MODY3: relative frequency and identification of seven novel germline mutations.Semantic proximity Read ↗

Clinical application of ACMG-AMP guidelines in HNF1A and GCK variants in a cohort of MODY families.Semantic proximity Read ↗

Genetic epidemiology of MODY in the Czech republic: new mutations in the MODY genes HNF-4alpha, GCK and HNF-1alpha.Semantic proximity Read ↗

Three novel mutations in MODY and its phenotype in three different Czech families.Semantic proximity Read ↗

Mutations in GCK and HNF-1alpha explain the majority of cases with clinical diagnosis of MODY in Spain.Semantic proximity Read ↗

HNF1alpha mutations are present in half of clinically defined MODY patients in South-Brazilian individuals.Semantic proximity Read ↗

HNF1 alpha gene coding regions mutations screening, in a Caucasian population clinically characterized as MODY from Argentina.Semantic proximity Read ↗

Three unreported glucokinase (GCK) missense mutations detected in the screening of thirty-two Brazilian kindreds for GCK and HNF1A-MODY.Semantic proximity Read ↗

De novo mutations of GCK, HNF1A and HNF4A may be more frequent in MODY than previously assumed.Semantic proximity Read ↗

Identification of a gain-of-function mutation in the HNF-1beta gene in a Japanese family with MODY.Semantic proximity Read ↗

Novel mutations in GCK and HNF1A genes in Italian families with MODY phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.