Cognitive functioning in affected sibling pairs with ADHD: familial clustering and dopamine genes.

doi:10.1111/j.1469-7610.2008.01928.x

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Article

Cognitive functioning in affected sibling pairs with ADHD: familial clustering and dopamine genes.

Journal of child psychology and psychiatry, and allied disciplines - 1 Sept 2008

Loo Sandra K, Rich Erika Carpenter, Ishii Janeen, McGough James, McCracken James, Nelson Stanley, Smalley Susan L

Abstract excerpt

BACKGROUND: This paper examines familiality and candidate gene associations of cognitive measures as potential endophenotypes in attention-deficit/hyperactivity disorder (ADHD). METHODS: The sample consists of 540 participants, aged 6 to 18, who were diagnosed with ADHD from 251 families recruited for a larger genetic study of ADHD. All members of the family underwent psychiatric interviews and children were...

Topics

Adolescent
Attention Deficit Disorder with Hyperactivity
Child
Cognition Disorders
Dopamine
Dopamine Plasma Membrane Transport Proteins
Female
Genotype
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neuropsychological Tests

Phenotype

Polymorphism, Genetic

Receptors, Dopamine D4

Receptors, Dopamine D5

Sibling Relations

Source

Open in PubMed

Identifiers

PMID: 18665883
DOI: 10.1111/j.1469-7610.2008.01928.x

Genes

DRD4
DRD5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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