Linking within- and between-host dynamics in the evolutionary epidemiology of infectious diseases.

Abstract excerpt

Nested models (also called embedded models) explicitly link dynamical processes that occur at different scales. Recently there has been considerable interest in linking within- and between-host levels of disease dynamics in the study of pathogen evolution. Here we review the extent to which these nested models have increased our understanding of pathogen evolution. We suggest that, although such models have been...

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