Article
Polymerase read-through at the first transcription termination site contributes to regulation of borna disease virus gene expression.
Journal of virology - 1 Oct 2008
Poenisch Marion, Wille Sandra, Staeheli Peter, Schneider Urs
Abstract excerpt
An unusually long noncoding sequence is located between the N gene of Borna disease virus (BDV) and the genes for regulatory factor X and polymerase cofactor P. Most of these nucleotides are transcribed and seem to control translation of the bicistronic X/P mRNA. We report here that Vero cells persistently infected with mutant viruses containing minor alterations in this control region showed almost normal levels...
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