An evaluation of PCR primer sets used for detection of <i>Propionibacterium acnes</i> in prostate tissue samples

Abstract excerpt

BACKGROUND: Multiple studies have now shown that Propionibacterium acnes can be cultured from post-prostatectomy derived prostate tissue samples. In contrast, both universal eubacterial 16S rDNA PCR and P. acnes-specific 16S rDNA PCR have failed to detect this organism at a frequency similar to that of bacterial culture. A potential explanation for this discrepancy, proposed by Cohen et al., involves mismatches...

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