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Detection of Macrolide Resistance in<i>Mycoplasma pneumoniae</i>by Real-Time PCR and High-Resolution Melt Analysis

22 Jul 2008

Abstract excerpt

Mycoplasma pneumoniae is a significant cause of community-acquired pneumonia, which is often empirically treated with macrolides or azalides such as erythromycin or azithromycin. Recent studies have discovered the existence of macrolide-resistant strains within the population that have been mapped to mutations within the domain V region of the 23S rRNA gene. Currently, identification of these resistant strains...

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PMID: 18644962
DOI: 10.1128/aac.00582-08

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