Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylation of the RUNX3 Promoter as a Potential Prognostic Marker for Bladder Tumor

19 Jul 2008

Abstract excerpt

PURPOSE: DNA methylation is a key regulator of gene transcription and genomic stability, and alterations in DNA methylation patterns are frequently detected in human tumors. Previously we reported that inactivation of RUNX3 by primarily epigenetic alterations in DNA methylation is closely associated with bladder tumor development, recurrence and progression. In the current series we evaluated the association...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18639281
DOI: 10.1016/j.juro.2008.05.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylation of the RUNX3 Promoter as a Potential Prognostic Marker for Bladder TumorPMID 18639281Read ↗

Tissue Inhibitor of Metalloproteinases-3 Promoter Methylation is an Independent Prognostic Factor for Bladder CancerSemantic proximity Read ↗

Epigenetic markers as promising prognosticators for bladder cancerSemantic proximity Read ↗

Predicting favourable prognosis of urothelial carcinoma: gene expression and genome profilingSemantic proximity Read ↗

Prognostic and Predictive Value of Epigenetic Biomarkers and Clinical Factors in Upper Tract Urothelial CarcinomaSemantic proximity Read ↗

A DNA hypermethylation profile reveals new potential biomarkers for the evaluation of prognosis in urothelial bladder cancerSemantic proximity Read ↗

Epigenetic biomarkers in urothelial bladder cancerSemantic proximity Read ↗

Prognostic relevance of methylation markers in patients with non-muscle invasive bladder carcinomaSemantic proximity Read ↗

KISS1 Methylation and Expression as Tumor Stratification Biomarkers and Clinical Outcome Prognosticators for Bladder Cancer PatientsSemantic proximity Read ↗

Aberrant Promoter Methylation of Multiple Genes during Pathogenesis of Bladder CancerSemantic proximity Read ↗

<i>RUNX3</i> Methylation Reveals that Bladder Tumors Are Older in Patients with a History of SmokingSemantic proximity Read ↗

FGFR3 overexpression is prognostic of adverse outcome for muscle-invasive bladder carcinoma treated with adjuvant chemotherapy.Semantic proximity Read ↗

Expression levels of FGFR3 as a prognostic marker for the progression of primary pT1 bladder cancer and its association with mutation statusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.