Article
Human platelet antigens polymorphisms and susceptibility of thrombosis in hemodialysis patients.
Hemodialysis international. International Symposium on Home Hemodialysis - 1 Jul 2008
Gorgi Yousr, Sfar Imen, Ben Aabdallah Taieb, Aouadi Houda, Abderrahim Ezzeddine, Bardi Rafika, Jendoubi-Ayed Saloua, Ayed Khaled
Abstract excerpt
To investigate the association between the polymorphisms of human platelet antigen (HPA)-1,2,3,4,5 and susceptibility to develop thrombosis accident in arteriovenous fistula (AVF), genomic DNA of 112 hemodialysis (HD) patients and 100 healthy blood donors were genotyped by PCR-SSP. The patients were classified into 2 groups: G1 included 54 HD patients presented at least one thrombotic episode on the level of the...
Topics
- Adult
- Antigens, Human Platelet
- Biomarkers
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Graft Occlusion, Vascular
- Humans
- Kidney Failure, Chronic
