Article
Using a multiplex polymerase chain reaction for the identification of Beijing strains of Mycobacterium tuberculosis.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Jan 2009
Sun J-R, Lee S-Y, Dou H-Y, Lu J-J
Abstract excerpt
The genotype of a Beijing strain of Mycobacterium tuberculosis (MTB) is usually determined by spoligotyping. However, this technique requires special equipment and is time-consuming. In this study, we developed a new multiplex polymerase chain reaction (PCR) to differentiate between Beijing and non-Beijing strains of MTB. A total of 323 MTB isolates were genotyped by both spoligotyping and the novel multiplex...
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