Article
Metabolomic strategies to identify tissue-specific effects of cardiovascular drugs.
Expert opinion on drug metabolism & toxicology - 1 Jun 2008
Jänis Minna T, Laaksonen Reijo, Oresic Matej
Abstract excerpt
BACKGROUND: The number of patients eligible for cardiovascular therapies in general is forecast to increase substantially in the coming decades. However, the current list of potential future cardiovascular blockbuster drugs is alarmingly short. There is thus a clear need for innovative strategies to increase the efficiency of drug development pipelines by establishing new sensitive biomarkers to monitor drug...
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